Transplantation medicine is considered a pacesetter for medical innovations. Aside from the development of highly complex surgical methods, interdisciplinary cooperation and close collaboration with basic medical research have always been necessary in order to master the challenges of transplantation medicine. Understanding the immune system as well as controlling tissue rejection through targeted medication were the prerequisites of our current ability to "routinely" perform transplants in the case of terminal organ failure. But beyond medical feasibility, transplantation medicine also has to wrestle with societal, ethical and legal problems. Questions related to distributive justice (utility principle versus urgency) or organ donation (e.g. presumed consent, organ donation after cerebral death, remunerated organ donation) require further transdisciplinary discussion in order to gain societal acceptance and legitimacy.Within the CAS Research Focus, these questions will be discussed with a broad interdisciplinary audience as well as socially, ethically and legally contextualized. The aim of the research focus is to establish an interdisciplinary network at LMU.